Thursday, September 20, 2012

Advances in Multiple Sclerosis and Experimental Demyelinating Diseases pdf

Advances in Multiple Sclerosis and Experimental Demyelinating Diseases



Author:
Edition: 1
Publisher: Springer
Binding: Hardcover
ISBN: 354073676X



Advances in Multiple Sclerosis and Experimental Demyelinating Diseases (Current Topics in Microbiology and Immunology)


There is a need for a paradigm shift in our thinking about the pathogenesis of multiple sclerosis. Medical books Advances in Multiple Sclerosis and Experimental Demyelinating Diseases . /P>

Challenging Charcot s hypothesis that inflammatory response is the primary contributor to demyelination, Dr. Rodriguez and colleagues take a fresh, bold look at the causes and possible treatments of MS.

Assuming oligodendrocyte injury as a prerequisite to MS, the authors explore viruses, toxins and genetic defects as possible culprits. They present novel methods to interrupt and reverse demyelination Medical books Advances In Multiple Sclerosis And Experimental Demyelinating Diseases - Rod. Electronics Cameras Computers Software Housewares Sports DVDs Music Books Games Toys in titles descriptions Company Info |Checkout Info |Shipping Info |Return Policy |FAQ's Add us as a favorite seller By continuing with your purchase using the eBay Buy It Now button, you agree to the Buy Terms of Use at http://stores.ebay.com/Buys-Internet-Superstore/Terms.html . Advances in Multiple Sclerosis and Experimental Demyelinating Diseases - Rodriguez, Moses (EDT)THIS IS A BRAND NEW UNOPENED ITEM. Des

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Electronics Cameras Computers Software Housewares Sports DVDs Music Books Games Toys in titles descriptions Company Info |Checkout Info |Shipping Info |Return Policy |FAQ's Add us as a favorite seller By continuing with your purchase using the eBay Buy It Now button, you agree to the Buy Terms of Use at http://stores.ebay.com/Buys-Internet-Superstore/Terms.html . Advances in Multiple Sclerosis and Experimental Demyelinating Diseases - Rodriguez, Moses (EDT)THIS IS A BRAND NEW UNOPENED ITEM. Des

Categories: Myelination, Demyelination, Multiple sclerosis. Contributors: Moses Rodriguez - Author. Format: Hardcover

Categories: Myelination, Demyelination, Multiple sclerosis. Contributors: Moses Rodriguez - Author. Format: Hardcover

Categories: Myelination, Demyelination, Multiple sclerosi. Contributors: Moses Rodriguez - Author. Format: Hardcover



Medical Book Advances in Multiple Sclerosis and Experimental Demyelinating Diseases



/P>

Challenging Charcot s hypothesis that inflammatory response is the primary contributor to demyelination, Dr. Rodriguez and colleagues take a fresh, bold look at the causes and possible treatments of MS.

Assuming oligodendrocyte injury as a prerequisite to MS, the authors explore viruses, toxins and genetic defects as possible culprits. They present novel methods to interrupt and reverse demyelination. This book examines the correlation between axonal loss and clinical deficits, including the implied role of the CD8+ T cell and perforin. It assesses proteases, specifically, kallikrein 6, which are strongly associated with active demyelination. By directing natural autoantibodies against oligodendrocytes that demonstrate remyelination in animal models, the authors envision clinical trials for remyelination enhancement.

As internationally recognized specialists in a wide range of MS disciplines, the authors explore genetic tools for identifying patients who are most likely to experience spontaneous remyelination. Epidemiology studies offer additional avenues of treatment. Examples include uric acid, statin drugs, estrogen and progesterone.

MS affects nearly 400,000 people in the United States, many of whom are between18 and 40 years of age. With their novel, multifaceted approach to basic science and their applications in understanding cause and treatment the authors offer help to clinicians and hope to patients.



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