Author:
Edition: 1
Publisher: Oxford University Press, USA
Binding: Paperback
ISBN: 0199637024
The Cytokine Network
Cytokines are soluble mediators of intercellular communication. Medical books The Cytokine Network. They contribute to a chemical signalling language that regulates development, tissue repair, haemopoiesis, inflammation and the immune response. Potent cytokine polypepides have pleiotropic activities and functional redundancy. They act in a complex network where one cytokine can influence the production of, and response to, many other cytokines. In the past five years, this bewildering array of more than 100 effector molecules and associated cell surface receptors has been simplified by study of cytokine and cytokine receptor structure; elucidation of convergent intracellular signalling pathways; and molecular genetics, and targeted gene disruption to 'knock-out' production of individual cytokines in mice Medical books The Cytokine Network and Immune Function. Cytokines are well characterized molecules that control the communication between cells Their importance in immunology is very critical for the control of the quantity and of the quality of each specific response against foreign antigens virus bacteria When the cytokine network is mis regulated disease can appear autoimmunity immunodeficiencies like in AIDS or cancer This comprehensive treatment of this exciting area of molecular medicine presents an informative description of the major cytokines together with coverage of their role in the different parts of the immune system and of their implication in immunopathology and will be of great interest to medical researchers and academics in the field Industrial researchers with an interest in immunology will also find this book useful
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Cytokines are well characterized molecules that control the communication between cells Their importance in immunology is very critical for the control of the quantity and of the quality of each specific response against foreign antigens virus bacteria When the cytokine network is mis regulated disease can appear autoimmunity immunodeficiencies like in AIDS or cancer This comprehensive treatment of this exciting area of molecular medicine presents an informative description of the major cytokines together with coverage of their role in the different parts of the immune system and of their impl
Categories: Cytokines. Contributors: Fran Balkwill - Author. Format: Paperback
Categories: Cytokines. Contributors: Fran Balkwill - Author. Format: Paperback
Categories: Cytokines. Contributors: Fran Balkwill - Author. Format: Paperback
Medical Book The Cytokine Network
They contribute to a chemical signalling language that regulates development, tissue repair, haemopoiesis, inflammation and the immune response. Potent cytokine polypepides have pleiotropic activities and functional redundancy. They act in a complex network where one cytokine can influence the production of, and response to, many other cytokines. In the past five years, this bewildering array of more than 100 effector molecules and associated cell surface receptors has been simplified by study of cytokine and cytokine receptor structure; elucidation of convergent intracellular signalling pathways; and molecular genetics, and targeted gene disruption to 'knock-out' production of individual cytokines in mice. It is also now clear that the pathophysiology of infectious, autoimmune and malignant disease can be partially explained by the induction of cytokines and the subsequent cellular response. Viral homologues exist for many cytokines and receptors and genetic variations in cytokine production may influence response to pathogenic stimuli. Cytokine and cytokine antagonists have shown therapeutic potential in a number of chronic and acute diseases. The Cytokine Network: Frontiers in Molecular Biology is not a survey of individual cytokines, but guides the reader through the latest research on the cytokine network as a whole covering genomics, signalling pathways, control of the immune response, and therapeutics.
