Author: David A. Hopwood
Edition: 1
Publisher: Oxford University Press, USA
Binding: Hardcover
ISBN: 019515066X
Streptomyces in Nature and Medicine: The Antibiotic Makers
This is an insiders account of 50 years of genetic studies of the soil-inhabiting microbes that produce most of the antibiotics used to treat infections, as well as anti-cancer, anti-parasitic and immunosuppressant drugs. Medical books Streptomyces in Nature and Medicine. The book begins by describing how these microbes the actinomycetes were discovered in the latter part of the nineteenth century, but remained a Cinderella group until, in the 1940s, they shot to prominence with the discovery of streptomycin, the first effective treatment for tuberculosis and only the second antibiotic, after penicillin, to become a medical marvel. There followed a massive effort over several decades to find further treatments for infectious diseases and cancer, tempered by the rise of antibiotic resistance consequent on antibiotic misuse and over-use. The book goes on to describe the discovery of gene exchange in the actinomycetes in the context of the rise of microbial genetics in the mid-20th century, leading to determination of the complete DNA sequence of a model member of the group at the turn of the millennium. There follow chapters in which the intricate molecular machinery that adapts the organisms metabolism and development to life in the soil, including antibiotic production, is illuminated by the DNA blueprint Medical books Streptomyces In Nature And Medicine - David A. Hopwood (hardcover). Powered by Frooition Pro Click here to view full size. Full Size Image Click to close full size. Streptomyces in Nature And Medicine - Book NEW Author(s): David A. Hopwood Format: Hardcover # Pages: 250 ISBN-13: 9780195150667 Published: 02/03/2007 Language: English Weight: 1.31 pounds Brand new book. About Us Payment Shipping Customer Service FAQs Welcome to MovieMars All items are Brand New. We offer unbeatable prices, quick shipping times and a wide selection second to none. Purchases come wi
Download link for Streptomyces In Nature And Medicine: The Antibiotic Makers By David A. Hopwo
Powered by Frooition Pro Click here to view full size. Full Size Image Click to close full size. Streptomyces in Nature And Medicine - Book NEW Author(s): David A. Hopwood Format: Hardcover # Pages: 250 ISBN-13: 9780195150667 Published: 02/03/2007 Language: English Weight: 1.31 pounds Brand new book. About Us Payment Shipping Customer Service FAQs Welcome to MovieMars All items are Brand New. We offer unbeatable prices, quick shipping times and a wide selection second to none. Purchases come wi
Streptomyces in Nature And Medicine
payment | shipping rates | returns Streptomyces in Nature and Medicine: The Antibiotic Makers Product Category :Books ISBN :019515066X Title :Streptomyces in Nature and Medicine: The Antibiotic Makers EAN :9780195150667 Authors :Hopwood, David A.Binding :Hardcover Publisher :Oxford University Press, USA Publication Date :2007-02-03 Pages :272 Signed :False First Edition :False Dust Jacket :False List Price (MSRP) :54.99 Height :0.8700 inches Width :6.3000 inches Length :9.2900 inches Weight :1.
Streptomyces in Nature And Medicine The Antibiotic Makers, ISBN-13: 9780195150667, ISBN-10: 019515066X
Medical Book Streptomyces in Nature and Medicine
The book begins by describing how these microbes the actinomycetes were discovered in the latter part of the nineteenth century, but remained a Cinderella group until, in the 1940s, they shot to prominence with the discovery of streptomycin, the first effective treatment for tuberculosis and only the second antibiotic, after penicillin, to become a medical marvel. There followed a massive effort over several decades to find further treatments for infectious diseases and cancer, tempered by the rise of antibiotic resistance consequent on antibiotic misuse and over-use. The book goes on to describe the discovery of gene exchange in the actinomycetes in the context of the rise of microbial genetics in the mid-20th century, leading to determination of the complete DNA sequence of a model member of the group at the turn of the millennium. There follow chapters in which the intricate molecular machinery that adapts the organisms metabolism and development to life in the soil, including antibiotic production, is illuminated by the DNA blueprint. Then come an up-to-the minute account of the use of genetic engineering to make novel, hybrid, antibiotics, and a topical description of techniques to learn the roles of the thousands of genes in a genome sequence, throwing a powerful light on the biology of the organisms and their harnessing for increasing antibiotic productivity. In the final chapter we return to the mycobacteria that cause tuberculosis and leprosy, the first actinomycetes to be discovered, and how methodology, in part derived from the study of the streptomycetes, is being applied to understand and control these still deadly pathogens.
