Author:
Edition: 1
Publisher: Wiley-Interscience
Binding: Hardcover
ISBN: 0471784915
Drug Transporters: Molecular Characterization and Role in Drug Disposition (Wiley Series in Drug Discovery and Development)
A comprehensive guide to drug transporters that influence the absorption, distribution, and elimination of drugs in the body
The development of powerful expression cloning and genome analysis techniques has facilitated the molecular identification and characterization of numerous transporters that play a crucial role in drug disposition. Medical books Drug Transporters. Explaining the principles of drug transport and the associated techniques, Drug Transporters: Molecular Characterization and Role in Drug Disposition:
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Provides a comprehensive overview of drug transporters
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Includes specific descriptions of transporter families, including substrate and inhibitor specificity, subcellular and tissue localization, mechanisms governing transport, species differences, the clinical implications of these transporters in human physiology and disease, and their role in drug distribution, elimination, and interactions in drug therapy
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Describes transporter-mediated drug disposition, a newly emerging field in drug therapy
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Gives a comprehensive summary of drug transport across biological membranes
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in the liver, brain, kidney, and intestine
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Provides balanced coverage of mechanistic aspects and functional outcomes
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Features chapters contributed by distinguished scientists in their specialty areas
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Provides sufficient detail to enable non-specialists to understand the principles and techniques
This authoritative guide is a practical hands-on desk reference for researchers in academia and the pharmaceutical industry and scientists in government agencies Medical books Drug Transporters: Molecular Characterization and Role in Drug Disposition. Categories: Biological Transport->physiology, Drug carriers (Pharmacy), Biological Transport->physiology. Contributors: Guofeng You - Editor. Format: Hardcover
Download link for Drug Transporters: Molecular Characterization and Role in Drug Disposition
Categories: Biological Transport->physiology, Drug carriers (Pharmacy), Biological Transport->physiology. Contributors: Guofeng You - Editor. Format: Hardcover
Categories: Biological Transport->physiology, Drug carriers (Pharmacy), Biological Transport->physiology. Contributors: Guofeng You - Editor. Format: Hardcover
"Drug Transporters" provides an overview of the most important transporter families for drug therapy. Each chapter is dedicated to a different transporter family, discussing tissue expression, substrates, inhibitors, knock-out mouse models and clinical studies.
Highlighting the internationally hot topic of pharmacogenomics and its influence on drug therapy, Pharmacogenomics of Human Drug Transporters reviews individual drug transporters, including specific transporter families and clinical implications. This book serves as a comprehensive guide to drug transporters that influence the absorption, distribution, and elimination of drugs in the body, and the reasons why individuals differ. The authors include sufficient detail to enable non-specialists to understand the principles and techniques and provides a practical, hands-on resource for researchers
Medical Book Drug Transporters
Explaining the principles of drug transport and the associated techniques, Drug Transporters: Molecular Characterization and Role in Drug Disposition:
*
Provides a comprehensive overview of drug transporters
*
Includes specific descriptions of transporter families, including substrate and inhibitor specificity, subcellular and tissue localization, mechanisms governing transport, species differences, the clinical implications of these transporters in human physiology and disease, and their role in drug distribution, elimination, and interactions in drug therapy
*
Describes transporter-mediated drug disposition, a newly emerging field in drug therapy
*
Gives a comprehensive summary of drug transport across biological membranes
*
in the liver, brain, kidney, and intestine
*
Provides balanced coverage of mechanistic aspects and functional outcomes
*
Features chapters contributed by distinguished scientists in their specialty areas
*
Provides sufficient detail to enable non-specialists to understand the principles and techniques
This authoritative guide is a practical hands-on desk reference for researchers in academia and the pharmaceutical industry and scientists in government agencies. It is also an excellent text for graduate-level courses in the pharmaceutical and pharmacology fields.
