Nucleic Acids in Innate Immunity pdf

Author:
Edition: 1
Publisher: CRC Press
Binding: Hardcover
ISBN: 1420068253

Nucleic Acids in Innate Immunity

Until recently, innate immunity was regarded as a relatively nonspecific system designed to engulf and destroy pathogens. Medical books Nucleic Acids in Innate Immunity. However, new studies show that the innate immune system is highly developed in its ability to discriminate between self and foreign entities. Understanding this mechanism can lead to therapeutic strategies based on manipulation of this previously unexploited branch of the immune system.

Drawing on the research of leading experts, Nucleic Acids in Innate Immunity provides insight in this new area of immunology. The book begins by explaining the roles of nucleic acids in immunity, describing the mechanism of discrimination based on pattern-recognition receptors (PRRs), including Toll-like receptors (TLRs), Nod-like receptors (NLR), and RIG-I-like receptors (RLR) Medical books Nucleic Acids in Innate Immunity. Categories: DNA, Natural immunity, Nucleic acids. Contributors: Ken J. Ishii - Editor. Format: Hardcover

Download link for Nucleic Acids in Innate Immunity

Categories: DNA, Natural immunity, Nucleic acids. Contributors: Ken J. Ishii - Editor. Format: Hardcover

Nucleic Acids in Innate Immunity, ISBN-13: 9781420068252, ISBN-10: 1420068253

Store Search search Title, ISBN and Author Nucleic Acids in Innate Immunity by Ken J. Ishii Estimated delivery 3-12 business days Format Hardcover Condition Brand New Until recently, innate immunity was regarded as a relatively nonspecific system designed to engulf and destroy pathogens. However, new studies show that the innate immune system is highly developed in its ability to discriminate between self and foreign entities. Understanding this mechanism can lead to therapeutic strategies base

"Until recently, innate immunity was regarded as a relatively nonspecific system designed to engulf and destroy pathogens. However, new studies show that the innate immune system is highly developed in its ability to discriminate between self and foreign entities. Understanding this mechanism can lead to therapeutic strategies based on manipulation of this previously unexploited branch of the immune system. Drawing on the research of leading experts, Nucleic Acids in Innate Immunity provides insight in this new area of immunology. The book begins by explaining the roles of nucleic acids in imm

Medical Book Nucleic Acids in Innate Immunity

However, new studies show that the innate immune system is highly developed in its ability to discriminate between self and foreign entities. Understanding this mechanism can lead to therapeutic strategies based on manipulation of this previously unexploited branch of the immune system.

Drawing on the research of leading experts, Nucleic Acids in Innate Immunity provides insight in this new area of immunology. The book begins by explaining the roles of nucleic acids in immunity, describing the mechanism of discrimination based on pattern-recognition receptors (PRRs), including Toll-like receptors (TLRs), Nod-like receptors (NLR), and RIG-I-like receptors (RLR). Chapters discuss how these PRRs recognize and respond to pathogen-associated molecular patterns (PAMPs) by activating specific signaling pathways.

The second section focuses on the therapeutic applications of immunomodulatory DNA by manipulating released pathogenic nucleic acids as immune system stimulants. The book introduces novel therapeutics developed to prevent or treat infectious diseases, allergic disorders, and cancer, as well as clearing unnecessary or abnormal host molecules.

The final section addresses how the immune system discriminates self and non-self RNA. Recent findings that host (self) nucleic acids are not inert in the immune system beg the question of exactly what elements within DNA or RNA are recognized by the innate immune system. Contributions review recent advances to understand innate immune recognition of nucleic acids and describe the resulting immune modulation.

Providing a comprehensive review of nucleic acid recognition and regulation by the innate immune system, this seminal work reveals new directions for future research in immune modulation.

Triple-Helical Nucleic Acids

Author: Valery N. Soyfer
Edition: 1996
Publisher: Springer
Binding: Hardcover
ISBN: 0387944958

Triple-Helical Nucleic Acids

The ability of DNA to exist in configurations other than its classical double-stranded form has been known for many years. Medical books Triple-Helical Nucleic Acids. There has been a spectacular recent surge of interest in these forms, notably in the three-stranded or triple-helical form. Triplex-like nucleic acids are now known to exist in vivo, and may well participate in significant biological processes. Interest in triple-helical nucleic acids has been greatly stimulated by their potential exploitation to control gene expression, serve as tools in genome mapping strategies, etc. The authors have written an encyclopedic introduction to nucleic acid triplexes based on many years of familiarity with the topic Medical books .

Medical Book Triple-Helical Nucleic Acids

There has been a spectacular recent surge of interest in these forms, notably in the three-stranded or triple-helical form. Triplex-like nucleic acids are now known to exist in vivo, and may well participate in significant biological processes. Interest in triple-helical nucleic acids has been greatly stimulated by their potential exploitation to control gene expression, serve as tools in genome mapping strategies, etc. The authors have written an encyclopedic introduction to nucleic acid triplexes based on many years of familiarity with the topic. The book includes information on chemistry, conformation, physical properties, applications, and hypotheses about the biological role of triplexes. It pays particular attention to the different methods for investigating these molecules, a feature which will be welcomed by those new to the field.

Fluorescent Energy Transfer Nucleic Acid Probes pdf

Author:
Edition: 2006
Publisher: Humana Press
Binding: Hardcover
ISBN: 1588293807

Fluorescent Energy Transfer Nucleic Acid Probes: Designs And Protocols (Methods in Molecular Biology) (Methods in Molecular Biology)

The first comprehensive treatment of energy transfer (ET) nucleic acid probes. Medical books Fluorescent Energy Transfer Nucleic Acid Probes. Medical books Fluorescent Energy Transfer Nucleic Acid Probes Desi..., 9781588293800. Fluorescent Energy Transfer Nucleic Acid Probes Designs And Protocols, ISBN-13: 9781588293800, ISBN-10: 1588293807

Download link for Fluorescent Energy Transfer Nucleic Acid Probes. Designs and Protocols

Fluorescent Energy Transfer Nucleic Acid Probes Designs And Protocols, ISBN-13: 9781588293800, ISBN-10: 1588293807

format hardback language english publication year 01 04 2006 series methods in molecular biology subject mathematics sciences subject 2 life sciences general title fluorescent energy transfer nucleic acid probes designs and protocols author vladimir v didenko publisher humana pr inc publication date mar 29 2006 pages 372 binding hardcover edition hardback cd rom dimensions 6 00 wx 9 00 hx 1 00 d isbn 1588293807 subject science life sciences biology molecular biology description molecular beaco

Store Search search Title, ISBN and Author Fluorescent Energy Transfer Nucleic Acid Probes: Designs and Protocols [With CDROM] Estimated delivery 3-12 business days Format Hardcover Condition Brand New The first comprehensive treatment of energy transfer (ET) nucleic acid probes. Hands-on experts thoroughly describe all the major probes, both fluorescence resonance energy transfer (FRET)-based and non-FRET-based, and provide a complete set of techniques to monitor DNA and RNA reactions, includi

Fluorescent Energy Transfer Nucleic Acid Probes: Designs and Protocols [With CDROM]

Medical Book Fluorescent Energy Transfer Nucleic Acid Probes

Hands-on experts thoroughly describe all the major probes, both fluorescence resonance energy transfer (FRET)-based and non-FRET-based, and provide a complete set of techniques to monitor DNA and RNA reactions, including hybridization, amplification, cleavage, folding, and associations with proteins, other molecules, and metal ions. Optimal design strategies for customized ET probes are presented, as well as techniques for distance determination in protein-DNA complexes and the detection of topological DNA alterations, mutations, DNA breaks and single nucleotide polymorphisms. Merging work on nanotechnology, and fluorescent probes, authors describe in detail the design and application of ET-using molecular devices, such as biosensors, molecular machines, and logic gates for molecular scale computation.

Nucleic Acids in Chemistry and Biology pdf

Author:
Edition: 2
Publisher: Oxford University Press, USA
Binding: Paperback
ISBN: 0199635331

Nucleic Acids in Chemistry and Biology

Since the discovery of the DNA double helix in 1953, nucleic acids have formed the central theme of much of contemporary molecular science. Medical books Nucleic Acids in Chemistry and Biology. Medical books Nucleic Acids in Chemistry and Biology. Categories: Nucleic acids. Contributors: G. Michael Blackburn - Editor. Format: Hardcover

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Categories: Nucleic acids. Contributors: G. Michael Blackburn - Editor. Format: Hardcover

Categories: Nucleic acids. Contributors: G. Michael Blackburn - Editor. Format: Hardcover

Categories: Nucleic acids. Contributors: G. Michael Blackburn - Editor. Format: Hardcover

Nucleic Acids in Chemistry and Biology (3rd Edition) by Blackburn, G. Michael/ Gait, Michael J./ Loakes, David [Hardcover]

Medical Book Nucleic Acids in Chemistry and Biology

Nowhere is this more apparent than in the increasing efforts to determine the DNA sequence of the human genome and the development of new diagnostics of genetic disease. Recent sophistication of nucleic acids synthesis has been key to the establishment of the biotechnology industry and our improving knowledge of nucleic acid structures and interactions is noticeably influencing the design of novel drugs.This second and completely revised edition draws on the expertise of the same international group of authors to set the basics of the nucleic acids in the context of the expanding horizons set by modern structural biology, RNA enzymology, drug discovery and biotechnology.