Saturday, September 10, 2011

Analysis of Complex Disease Association Studies pdf

Analysis of Complex Disease Association Studies



Author:
Edition: 1
Publisher: Academic Press
Binding: Hardcover
ISBN: 012375142X



Analysis of Complex Disease Association Studies: A Practical Guide


According to the National Institute of Health, a genome-wide association study is defined as any study of genetic variation across the entire human genome that is designed to identify genetic associations with observable traits (such as blood pressure or weight), or the presence or absence of a disease or condition. Medical books Analysis of Complex Disease Association Studies. Whole genome information, when combined with clinical and other phenotype data, offers the potential for increased understanding of basic biological processes affecting human health, improvement in the prediction of disease and patient care, and ultimately the realization of the promise of personalized medicine. In addition, rapid advances in understanding the patterns of human genetic variation and maturing high-throughput, cost-effective methods for genotyping are providing powerful research tools for identifying genetic variants that contribute to health and disease. (good paragraph)

This burgeoning science merges the principles of statistics and genetics studies to make sense of the vast amounts of information available with the mapping of genomes. In order to make the most of the information available, statistical tools must be tailored and translated for the analytical issues which are original to large-scale association studies Medical books Analysis Of Complex Disease Association Studies: A Practical Guide Zeggini, Elef. format hardback language english publication year 17 11 2010 subject medicine subject 2 medicine general title analysis of complex disease association studies a practical guide author zeggini eleftheria publisher academic pr publication date oct 20 2010 pages 331 binding hardcover edition 1 st dimensions 6 00 wx 9 00 hx 1 00 d isbn 012375142 x subject medical diseases brand new hardcover all orders get full access to our online status tracking service allowing you to view realtime order progre

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format hardback language english publication year 17 11 2010 subject medicine subject 2 medicine general title analysis of complex disease association studies a practical guide author zeggini eleftheria publisher academic pr publication date oct 20 2010 pages 331 binding hardcover edition 1 st dimensions 6 00 wx 9 00 hx 1 00 d isbn 012375142 x subject medical diseases brand new hardcover all orders get full access to our online status tracking service allowing you to view realtime order progre

Analysis of Complex Disease Association Studies : A Practical Guide, ISBN-13: 9780123751423, ISBN-10: 012375142X

Analysis of Complex Disease Association Studies (Hardcover)

Analysis of Complex Disease Association Studies: A Practical Guide



Medical Book Analysis of Complex Disease Association Studies



Whole genome information, when combined with clinical and other phenotype data, offers the potential for increased understanding of basic biological processes affecting human health, improvement in the prediction of disease and patient care, and ultimately the realization of the promise of personalized medicine. In addition, rapid advances in understanding the patterns of human genetic variation and maturing high-throughput, cost-effective methods for genotyping are providing powerful research tools for identifying genetic variants that contribute to health and disease. (good paragraph)

This burgeoning science merges the principles of statistics and genetics studies to make sense of the vast amounts of information available with the mapping of genomes. In order to make the most of the information available, statistical tools must be tailored and translated for the analytical issues which are original to large-scale association studies. This book will provide researchers with advanced biological knowledge who are entering the field of genome-wide association studies with the groundwork to apply statistical analysis tools appropriately and effectively. With the use of consistent examples throughout the work, chapters will provide readers with best practice for getting started (design), analyzing, and interpreting data according to their research interests. Frequently used tests will be highlighted and a critical analysis of the advantages and disadvantage complimented by case studies for each will provide readers with the information they need to make the right choice for their research. Additional tools including links to analysis tools, tutorials, and references will be available electronically to ensure the latest information is available.

* Easy access to key information including advantages and disadvantage of tests for particular applications, identification of databases, languages and their capabilities, data management risks, frequently used tests
* Extensive list of references including links to tutorial websites
* Case studies and Tips and Tricks

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